Gangrene is tissue death due to lack of blood circulation in the affected area.
Gangrene can affect tissues from internal organs or can affect fingers, hands or feet.
If gangrene is on the surface, there are changes in skin color, it becomes darker to bluish-black.
In the affected area there may also appear different suppurations.
Pain occurs in the affected area and is severe, unbearable.
Also in that area the local temperature is low and sensitivity of the area disappears. It may even occur the inability to move the affected limb.
In case of the damage of internal organs patient shows a malaise, a feeling of confusion, complaining of severe pain in the affected organ and signs of hypotension.